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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Hemoglobin F has a high affinity for oxygen. When Hb F is elevated, cells containing Hb S are more oxygenated and do not sickle as readily as they would if Hb F were not present or present in small quantities.
Which hemoglobin, when elevated, acts as a protection against sickling in patients with HbS?

A) Hemoglobin C
B) Hemoglobin F
C) Hemoglobin G
D) Hemoglobin A2

2. 1. B
2. D
3. A
4. C
Red to Brown Urine: porphobilinogen, hematuria, myoglobinuria, etc.
Green: Food colorings; Increased carotene in the diet;
Pseudomonas aeruginosa infection
Yellow: bilirubin, bile pigments
White: phosphates, other crytals
Match urine color with substance that might have been responsible:
1. Phosphates
2. Bilirubin
3. Pseudomonas
4. Porphobilinogen

A) Red to brown
B) Blue to green
C) White
D) Yellow

3. Which of the following CD markers is NOT present on a normal mature T cell?

A) CD20
B) CD3
C) CD5
D) CD7

4. Hemoglobin H is a tetramer made of four beta globin chains. Hemoglobin H occurs when there is very limited alpha chain availability used to make normal hemoglobin A. Hemoglobin H forms in those affected with alpha thalassemia major as well as in people with the combination of two-gene deletion alpha thalassemia and hemoglobin Constant Spring.
Hematology
Which of the following combination of globin chains comprise Hemoglobin H?

A) 4 beta chains
B) 4 alpha chains
C) 2 alpha, 2 beta
D) 2 alpha, 2 gamma

5. Certain recipients have increased risk for developing TA-GVHD. They are:
Neonates less than 4 months of age
Fetuses
Recipients with a congenital or acquired immunodeficiency, such as bone marrow or stem cell recipients, and patients receiving chemotherapy recipients of donor units from a blood relative Which of the following patients are at risk for transfusion-associated graft versus host disease (TA-GVHD) and require irradiated cellular blood products? (Choose all that apply)

A) Patients with a history of allergic reactions.
B) Patients with chronic anemias.
C) Recipients of donor units known to be from a blood relative.
D) Neonates less than 4 months of age
E) Patient receiving chemotherapy who are immunocompromised.

Solutions: